Synthesis and Biological Activities of 2-Amino-2-deoxy- and 6-Amino-6-deoxy-α-D-glucopyranosyl-2,5-dideoxystreptamines
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Synthesis and conformational analysis of 6-C-methyl-substituted 2-acetamido-2-deoxy-beta-D-glucopyranosyl mono- and disaccharides.
Several 6-C-substituted 2-acetamido-2-deoxy-beta-D-glucopyranosides (beta-D-GlcNAc monosaccharides 1a-3a and 1,4-linked disaccharides 1b-3b) were studied by solution NMR spectroscopy. Conformational analysis of the (6S)- and (6R)-C-methyl-substituted beta-d-GlcNAc monosaccharides indicates that the stereodefined methyl groups impose predictable conformational biases on the exocyclic C-5-C-6 bon...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1976
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.49.1975